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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NDC80
All Species:
21.52
Human Site:
Y458
Identified Species:
36.41
UniProt:
O14777
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14777
NP_006092.1
642
73913
Y458
V
K
Y
R
A
Q
V
Y
V
P
L
K
E
L
L
Chimpanzee
Pan troglodytes
XP_512046
642
73980
Y458
V
K
Y
R
A
Q
V
Y
V
P
L
K
E
L
L
Rhesus Macaque
Macaca mulatta
XP_001086615
642
73921
Y458
V
K
Y
R
A
Q
V
Y
V
P
L
K
E
L
L
Dog
Lupus familis
XP_537313
642
73907
Y458
V
K
Y
R
A
Q
V
Y
V
P
L
K
E
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0F1
642
73943
Y458
V
K
Y
R
T
Q
V
Y
A
P
L
K
E
L
L
Rat
Rattus norvegicus
NP_001119742
329
38011
E154
P
L
K
E
L
L
N
E
I
E
E
E
I
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505423
649
75199
Y460
V
K
Y
R
T
Q
I
Y
V
P
L
K
E
R
L
Chicken
Gallus gallus
Q76I89
640
73723
K461
V
K
Y
R
T
Q
I
K
A
P
L
M
E
I
V
Frog
Xenopus laevis
Q8AWF5
638
74459
N456
M
H
Y
R
N
K
I
N
V
P
L
V
E
I
L
Zebra Danio
Brachydanio rerio
Q6DRJ7
632
73198
Q452
T
Q
Y
K
T
Q
I
Q
N
P
L
K
N
M
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17635
590
68894
P415
N
I
Q
M
N
L
E
P
L
R
A
P
T
N
E
Sea Urchin
Strong. purpuratus
XP_001197919
631
72734
D456
T
Q
H
S
P
M
L
D
F
V
S
T
I
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40460
691
80469
L510
E
G
I
S
Y
E
Q
L
F
P
K
G
S
G
I
Red Bread Mold
Neurospora crassa
Q96U60
743
84837
G535
Q
G
V
L
G
P
N
G
Q
P
L
G
G
V
E
Conservation
Percent
Protein Identity:
100
99.6
99.2
92.5
N.A.
83.9
44.5
N.A.
75.5
71.3
56.8
44.2
N.A.
N.A.
N.A.
21.8
28
Protein Similarity:
100
99.6
99.5
97.1
N.A.
91.5
47.9
N.A.
87.9
84.7
77.4
63.8
N.A.
N.A.
N.A.
44.8
51.2
P-Site Identity:
100
100
100
100
N.A.
86.6
0
N.A.
80
53.3
46.6
33.3
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
13.3
N.A.
86.6
73.3
73.3
66.6
N.A.
N.A.
N.A.
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
22.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
44.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
29
0
0
0
15
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
8
0
8
8
8
0
8
8
8
58
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% F
% Gly:
0
15
0
0
8
0
0
8
0
0
0
15
8
8
0
% G
% His:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
29
0
8
0
0
0
15
15
8
% I
% Lys:
0
50
8
8
0
8
0
8
0
0
8
50
0
8
8
% K
% Leu:
0
8
0
8
8
15
8
8
8
0
72
0
0
36
50
% L
% Met:
8
0
0
8
0
8
0
0
0
0
0
8
0
8
8
% M
% Asn:
8
0
0
0
15
0
15
8
8
0
0
0
8
15
0
% N
% Pro:
8
0
0
0
8
8
0
8
0
79
0
8
0
0
8
% P
% Gln:
8
15
8
0
0
58
8
8
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
58
0
0
0
0
0
8
0
0
0
8
0
% R
% Ser:
0
0
0
15
0
0
0
0
0
0
8
0
8
0
0
% S
% Thr:
15
0
0
0
29
0
0
0
0
0
0
8
8
0
0
% T
% Val:
50
0
8
0
0
0
36
0
43
8
0
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
65
0
8
0
0
43
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _